Article
Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer.
The International journal of biological markers - 4 May 2017
Vidigal Verônica Marques, Silva Tiago Donizetti, de Oliveira Juliana, Pimenta Célia Aparecida Marques, Felipe Aledson Vitor, Forones Nora Manoukian
Abstract excerpt
INTRODUCTION: Vitamin D receptor (VDR) and proteins encoded by the genes CYP27B2 and CYP24A1 involved in the production and inactivation of vitamin D can influence vitamin D and the susceptibility to colorectal cancer (CRC). The objective of this study was to investigate the relationship between the risk of CRC and polymorphisms in VDR, CYP27B1 and CYP24A1, lifestyle and dietary habits. METHODS: The study...
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