Article
Dietary calcium, vitamin D, VDR genotypes and colorectal cancer.
International journal of cancer - 20 Sept 2004
Slattery Martha L, Neuhausen Susan L, Hoffman Michael, Caan Bette, Curtin Karen, Ma Khe Ni, Samowitz Wade
Abstract excerpt
The vitamin D receptor (VDR) may importantly modulate risk of colorectal cancer either independently or in conjunction with calcium and vitamin D intake. We evaluate the association between calcium, vitamin D, dairy products, and VDR polymorphisms in 2 case-control studies of colon and rectal cancer (n = 2,306 cases and 2,749 controls). Dietary intake was evaluated using a detailed diet history questionnaire. Two...
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