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Article

Association of vitamin D receptor gene variants, adiposity and colon cancer.

Carcinogenesis - 1 Sept 2008

Ochs-Balcom Heather M, Cicek Mine S, Thompson Cheryl L, Tucker Thomas C, Elston Robert C, J Plummer Sarah, Casey Graham, Li Li

Abstract excerpt

Vitamin D receptor (VDR) gene variants have been variably associated with risk of colon cancer in epidemiologic studies. We sought to further clarify the relationship between colon cancer and three single-nucleotide polymorphisms (SNPs) in the VDR gene (Cdx-2, FokI and TaqI) in a population-based case-control study of 250 incident cases and 246 controls. Colon cancer cases were more frequently homozygous for the...

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Share to Adiposity
Share to Body Mass Index
Share to CDX2 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Receptors, Calcitriol

Share to Site-Specific DNA-Methyltransferase (Adenine-Specific)

Share to Taq Polymerase

Share to Vitamin D

Source

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Identifiers

PMID: 18628249
DOI: 10.1093/carcin/bgn166
PMCID: PMC2722851

Genes

VDR

Provenance

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