Article
Differential roles for snapin and synaptotagmin in the synaptic vesicle cycle.
PloS one - 1 Jan 2013
Yu Szi-Chieh, Klosterman Susan M, Martin Ashley A, Gracheva Elena O, Richmond Janet E
Abstract excerpt
Evoked synaptic transmission is dependent on interactions between the calcium sensor Synaptotagmin I and the SNARE complex, comprised of Syntaxin, SNAP-25, and Synaptobrevin. Recent evidence suggests that Snapin may be an important intermediate in this process, through simultaneous interactions of Snapin dimers with SNAP-25 and Synaptotagmin. In support of this model, cultured neurons derived from embryonically...
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