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Article

Snapin facilitates the synchronization of synaptic vesicle fusion.

Neuron - 12 Feb 2009

Pan Ping-Yue, Tian Jin-Hua, Sheng Zu-Hang

Abstract excerpt

Synaptic vesicle (SV) fusion is a fine-tuned process requiring a concert of fusion machineries. Using cortical neurons from snapin-deficient mice, we reveal a role for Snapin in facilitating synchronous release. In addition to reduced frequency of miniature excitatory postsynaptic currents (mini-EPSCs) and smaller release-ready vesicle pool (RRP) size, snapin deficiency results in EPSCs with multiple peaks and...

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Share to Excitatory Postsynaptic Potentials
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19217378
DOI: 10.1016/j.neuron.2008.12.029
PMCID: PMC2656773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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