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Article

Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma

1 Feb 1990

Abstract excerpt

By restriction fragment length polymorphism analysis, we examined loss of heterozygosity at 34 loci on 23 chromosomes in 35 surgically resected human hepatocellular carcinomas. Allele losses at the HP locus on chromosome 16q22 and at the MT2P1 locus on chromosome 4p11-q21 were detected in 57% (8/14) and 50% (8/16) of cases, respectively. Loss of heterozygosity on chromosomes 16q and 4 occurred simultaneously in 4...

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PMID: 1970554
DOI: 10.1111/j.1349-7006.1990.tb02534.x

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Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular CarcinomaPMID 1970554Read ↗

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