Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma.

doi:10.1073/pnas.87.17.6791

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1990

Tsuda H, Zhang W D, Shimosato Y, Yokota J, Terada M, Sugimura T, Miyamura T, Hirohashi S

Abstract excerpt

Loss of heterozygosity on chromosome 16 is a common genetic alteration in human hepatocellular carcinoma (HCC). To clarify the pathogenetic significance of allele loss on chromosome 16, we performed restriction fragment length polymorphism analysis of 70 surgically resected tumors by using 15 pol...

Topics

Alleles
Carcinoma, Hepatocellular
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 16
DNA Probes
DNA, Viral
Hepatitis B virus
Heterozygote
Humans
Liver
Liver Cirrhosis
Liver Neoplasms
Liver Regeneration
Models, Biological

Source

Open in PubMed Open full text

Identifiers

PMID: 2168560
DOI: 10.1073/pnas.87.17.6791
PMCID: PMC54623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2168560-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics