Variations of cervical vertebrae after expression of a Hox-1.1 transgene in mice.

doi:10.1016/0092-8674(90)90810-2

Back to search

Article

Variations of cervical vertebrae after expression of a Hox-1.1 transgene in mice.

Cell - 20 Apr 1990

Kessel M, Balling R, Gruss P

Abstract excerpt

To understand the function of murine homeobox genes, a genetic analysis is mandatory. We generated gain-of-function mutants by introducing genomic sequences of the Hox-1.1 gene under the control of a chicken beta-actin promoter into mice. Our previous data had shown that these transgenic mice are...

Topics

Animals
Animals, Newborn
Cervical Vertebrae
Genes, Homeobox
Genetic Vectors
Mice
Mice, Transgenic
Phenotype

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.