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Article

Graves' ophthalmopathy and gene polymorphisms in interleukin-1alpha, interleukin-1beta, interleukin-1 receptor and interleukin-1 receptor antagonist.

Clinical & experimental ophthalmology - 1 Aug 2009

Khalilzadeh Omid, Anvari Mehdi, Esteghamati Alireza, Mahmoudi Mahdi, Tahvildari Maryam, Rashidi Armin, Khosravi Farideh, Amirzargar Aliakbar

Abstract excerpt

PURPOSE: Interleukin-1 (IL-1) is known to have an important role in pathogenesis of Graves' ophthalmopathy (GO). Polymorphisms in IL-1 gene have been associated with autoimmune reactions. This study aimed to investigate the association of GO with single-nucleotide polymorphisms (SNPs) in the IL-1 family (IL-1alpha, IL-1beta, IL-1 receptor [IL-1R] and IL-1 receptor antagonist [IL-1RA]). METHODS: A total of 57...

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Identifiers

PMID: 19702713
DOI: 10.1111/j.1442-9071.2009.02093.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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