Article
Polymorphisms in IL-1beta and IL-1 receptor antagonist genes are associated with myasthenia gravis.
Journal of neuroimmunology - 1 Jan 1998
Huang D, Pirskanen R, Hjelmström P, Lefvert A K
Abstract excerpt
Interleukin 1 (IL-1)beta, TaqI restriction fragment length polymorphism (RFLP) in exon 5 and IL-1 receptor antagonist (IL-1Ra) polymorphism, variable numbers of an 86-bp tandem repeat (VNTR), were analysed in 107 patients with myasthenia gravis (MG) and 82 ethnically matched healthy control (HC) individuals. Positive association was found with IL-1beta TaqI RFLP allele 2 carriage in MG (OR = 2.007), while allele...
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