Article
Graves' disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ.
Endocrine - 1 Apr 2010
Anvari Mehdi, Khalilzadeh Omid, Esteghamati Alireza, Momen-Heravi Fatemeh, Mahmoudi Mahdi, Esfahani Shadi Abdar, Rashidi Armin, Amirzargar Aliakbar
Abstract excerpt
The role of genetic factors in the pathogenesis of Graves' disease (GD) is not clear. The purpose of this study was to investigate the association between single nucleotide polymorphisms in pro-inflammatory cytokine genes and GD in Iranian patients. A case-control hospital-based study was carried out on 107 GD patients and 140 healthy controls. Cytokine typing was performed by polymerase chain reaction with...
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