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Article

Interleukin-1-beta gene, but not the interleukin-1 receptor antagonist gene, is associated with Graves' disease.

Journal of clinical laboratory analysis - 1 Jan 2005

Chen Rong-Hsing, Chen Wen-Chi, Chang Chwen-Tzuei, Tsai Chang-Hai, Tsai Fuu-Jen

Abstract excerpt

Interleukin-1 (IL-1) is considered to be involved in the pathogenesis of Graves' disease. The aim of this study was to test whether the IL-1-beta gene promoter region and exon 5 and IL-1 receptor antagonist (IL-1Ra) gene intron 2 polymorphisms could be useful genetic markers for susceptibility to Graves' disease. A normal control group of 163 healthy people and another group of 95 patients with Graves' disease...

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Identifiers

PMID: 16025481
DOI: 10.1002/jcla.20067
PMCID: PMC6807985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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