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Plasmodium falciparum circumsporozoite protein: epidemiological variations among field isolates prevalent in India.

Tropical medicine & international health : TM & IH - 1 Aug 2009

Singh J P N, Verma S, Bhattacharya P R, Srivastava N, Dash A P, Biswas S

Abstract excerpt

OBJECTIVE: To investigate the extent of genetic variations in T-helper-cell epitopic regions of circumsporozoite (CS) protein in Plasmodium falciparum field isolates collected from different regions of India at different phases of malaria transmission. METHODS: Genomic DNA was isolated from 507 P. falciparum wild-parasite isolates obtained from six geographical locations of India at three time points coinciding...

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PMID: 19702596
DOI: 10.1111/j.1365-3156.2009.02314.x

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