Article
Genetic polymorphism of falciparum malaria vaccine candidate antigen genes among field isolates in India.
The American journal of tropical medicine and hygiene - 1 Jul 1999
Ranjit M R, Sharma Y D
Abstract excerpt
The present study was designed to investigate the genetic diversity of Plasmodium falciparum among field isolates from India. A total of 71 clinical isolates were analyzed by the polymerase chain reaction (PCR) for the amplification of repeat regions of malaria vaccine candidate antigen genes, i.e., merozoite surface antigen-1 (MSA-1), MSA-2, and circumsporozoite protein (CSP). All three genes showed variation;...
Topics
- Alleles
- Animals
- Antigens, Protozoan
- DNA Primers
- DNA, Protozoan
- Electrophoresis, Agar Gel
- Humans
- India
- Malaria Vaccines
- Malaria, Falciparum
- Merozoite Surface Protein 1
