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Article

Genetic polymorphism of falciparum malaria vaccine candidate antigen genes among field isolates in India.

The American journal of tropical medicine and hygiene - 1 Jul 1999

Ranjit M R, Sharma Y D

Abstract excerpt

The present study was designed to investigate the genetic diversity of Plasmodium falciparum among field isolates from India. A total of 71 clinical isolates were analyzed by the polymerase chain reaction (PCR) for the amplification of repeat regions of malaria vaccine candidate antigen genes, i.e., merozoite surface antigen-1 (MSA-1), MSA-2, and circumsporozoite protein (CSP). All three genes showed variation;...

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PMID: 10432065
DOI: 10.4269/ajtmh.1999.61.103

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