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Article

Antigenic repertoire of Plasmodium vivax transmission-blocking vaccine candidates from the Indian subcontinent.

Malaria journal - 2 May 2011

Prajapati Surendra K, Joshi Hema, Dua Virendra K

Abstract excerpt

BACKGROUND: Genetic polymorphism is an inevitable component of a multistage infectious organism, such as the malaria parasite. By means of genetic polymorphism, parasite opts particular polymorph and reveals survival advantage. Pvs25 and pvs28 are sexual stage antigen genes, expressed at the ookinete stage inside the mosquito gut, and considered as potential transmission-blocking vaccine candidates. This study...

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Identifiers

PMID: 21535892
DOI: 10.1186/1475-2875-10-111
PMCID: PMC3104378

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