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Article

Circumsporozoite protein gene diversity among temperate and tropical Plasmodium vivax isolates from Iran.

Tropical medicine & international health : TM & IH - 1 May 2006

Zakeri Sedigheh, Abouie Mehrizi Akram, Djadid Navid Diparast, Snounou Georges

Abstract excerpt

To date, there is no information on the genetic diversity of the circumsporozoite protein (CSP), a leading vaccine candidate, in Plasmodium vivax populations circulating in Iran. The gene for this protein, Pvcsp, was amplified from 374 P. vivax isolates collected in the temperate northern, and in the tropical southern endemic areas. PCR-RFLP analysis of the repeated central region revealed that the parasites...

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Identifiers

PMID: 16640626
DOI: 10.1111/j.1365-3156.2006.01613.x

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