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Article

Plasmodium falciparum: restricted polymorphism of T cell epitopes of the circumsporozoite protein in Brazil.

Experimental parasitology - 1 Nov 1990

Yoshida N, Di Santi S M, Dutra A P, Nussenzweig R S, Nussenzweig V, Enea V

Abstract excerpt

We examined the extent of variation of the 3' region of the circumsporozoite gene among Plasmodium falciparum isolates through amplification of a selected DNA fragment followed by DNA sequencing. A total of 32 isolates were analyzed, of which 24 were from Amazon endemic areas in Brazil and 8 from widely separated geographical regions in the world. Among Brazilian isolates only 2 variants were detected: 19...

Topics

Amino Acid Sequence
Animals
Antigens, Protozoan
Base Sequence
Brazil
DNA, Protozoan
Electrophoresis, Agar Gel
Epitopes
Genetic Variation
Molecular Sequence Data
Plasmodium falciparum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Protozoan Proteins

T-Lymphocytes

Source

Identifiers

PMID: 1699781
DOI: 10.1016/0014-4894(90)90064-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1699781-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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