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Article

Differential effects of ketoprofen on the pharmacokinetics of sulphadimethoxine in fast and slow acetylator rabbits.

The Journal of pharmacy and pharmacology - 1 Jan 1990

Imamura Y, Mori H, Otagiri M

Abstract excerpt

Intravenously co-administered ketoprofen decreased the plasma concentration of sulpha-dimethoxine (SDM) after intravenous bolus administration to fast acetylator rabbits, and significantly increased the total body clearance (CLtot) and steady-state volume of distribution (Vdss) of SDM. On the oth...

Topics

Acetylation
Animals
Injections, Intravenous
Ketoprofen
Male
Phenotype
Rabbits
Sulfadimethoxine

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1969955
DOI: 10.1111/j.2042-7158.1990.tb05353.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1969955-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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