Article
Characterization of arylamine acetyltransferase in the rabbit eye.
Investigative ophthalmology & visual science - 1 Jul 1991
Campbell D A, Schoenwald R D, Duffel M W, Barfknecht C F
Abstract excerpt
The activity of arylamine acetyltransferase with p-aminobenzoic acid (PABA), sulfamethazine (SMZ), and aminozolamide as substrates was studied in rabbit tissue homogenates of the corneal epithelium, stroma-endothelium, iris-ciliary process, and liver. Rabbits were classified as rapid or slow acetylators with respect to their rate of hepatic acetylation of SMZ. The ocular disposition of aminozolamide in the two...
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