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Article

Ala92 type 2 deiodinase allele increases risk for the development of hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 2007

Gumieniak Olga, Perlstein Todd S, Williams Jonathan S, Hopkins Paul N, Brown Nancy J, Raby Benjamin A, Williams Gordon H

Abstract excerpt

Accumulating evidence suggests that genes of the hypothalamic-pituitary-thyroid pathway influence susceptibility to hypertension. Type 2 iodothyronine deiodinase is responsible for the conversion of thyroxine to tri-iodothyronine for use in peripheral tissues. The present study evaluated whether a type 2 iodothyronine deiodinase nonsynonymous polymorphism, threonine 92 to alanine (Thr92Ala), is a determinant of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17224473
DOI: 10.1161/01.HYP.0000256295.72185.fd

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ala92 type 2 deiodinase allele increases risk for the development of hypertension.PMID 17224473Read ↗

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