Article
Association between interleukin 1 gene cluster polymorphisms and bilateral distal interphalangeal osteoarthritis.
The Journal of rheumatology - 1 Sept 2009
Solovieva Svetlana, Kämäräinen Olli-Pekka, Hirvonen Ari, Hämäläinen Satu, Laitala Mari, Vehmas Tapio, Luoma Katariina, Näkki Annu, Riihimäki Hilkka, Ala-Kokko Leena, Männikkö Minna, Leino-Arjas Päivi
Abstract excerpt
OBJECTIVE: To examine the association of the interleukin 1 gene (IL1) cluster polymorphisms and their haplotypes with bilateral distal interphalangeal joint osteoarthritis (DIP OA). METHODS: Radiographs of both hands of 295 dentists and 248 teachers were examined and classified for the presence of OA using reference images. Bilateral DIP OA was defined by the presence of radiographic findings of grade 2 or more...
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