Article
Association between the interleukin-1 family gene cluster and psoriatic arthritis.
Arthritis and rheumatism - 1 Jul 2006
Rahman Proton, Sun Shuying, Peddle Lynette, Snelgrove Tara, Melay William, Greenwood Celia, Gladman Dafna
Abstract excerpt
OBJECTIVE: The interleukin-1 (IL-1) cytokine elicits a wide variety of biologic activities that initiate and promote an inflammatory response. The loci in the IL1 gene cluster have recently been associated with ankylosing spondylitis (AS). Since there is clinical and immunologic overlap between psoriatic arthritis (PsA) and AS, we wanted to examine the association between a panel of single-nucleotide...
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