Article
Associations of the interleukin-1 gene locus polymorphisms with risk to hip and knee osteoarthritis: gender and subpopulation differences.
Scandinavian journal of immunology - 1 Feb 2013
Kaarvatn M H, Jotanovic Z, Mihelic R, Etokebe G E, Mulac-Jericevic B, Tijanic T, Balen S, Sestan B, Dembic Z
Abstract excerpt
Genetic predisposition to the complex hereditary disease like osteoarthritis (OA) of the large joints (hip and knee) includes the interleukin-1 gene (IL-1) cluster on chromosome 2. Using a case-control study with 500 OA patients (240 knee and 260 hip OA patients, all with joint replacement), we analysed frequencies of IL-1 gene cluster polymorphisms in Croatian Caucasian population. The control samples came from...
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