Article
Allelic variants of IL1R1 gene associate with severe hand osteoarthritis.
BMC medical genetics - 30 Mar 2010
Näkki Annu, Kouhia Sanna T, Saarela Janna, Harilainen Arsi, Tallroth Kaj, Videman Tapio, Battié Michele C, Kaprio Jaakko, Peltonen Leena, Kujala Urho M
Abstract excerpt
BACKGROUND: In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to severe OA of distal interphalangeal joints (DIP) in o...
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