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Article

Allelic variants of IL1R1 gene associate with severe hand osteoarthritis.

BMC medical genetics - 30 Mar 2010

Näkki Annu, Kouhia Sanna T, Saarela Janna, Harilainen Arsi, Tallroth Kaj, Videman Tapio, Battié Michele C, Kaprio Jaakko, Peltonen Leena, Kujala Urho M

Abstract excerpt

BACKGROUND: In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to severe OA of distal interphalangeal joints (DIP) in our genome wide scan families. METHODS: We genotyped 32 single nucleotide polymorphisms (SNPs) in this 470 kb region...

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Identifiers

PMID: 20353565
DOI: 10.1186/1471-2350-11-50
PMCID: PMC2859817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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