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Article

Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis.

Arthritis research & therapy - 1 Jan 2008

Kämäräinen Olli-Pekka, Solovieva Svetlana, Vehmas Tapio, Luoma Katariina, Riihimäki Hilkka, Ala-Kokko Leena, Männikkö Minna, Leino-Arjas Päivi

Abstract excerpt

INTRODUCTION: The objective of this study was to investigate the relationship of the IL-6 promoter variants G-597A, G-572C and G-174C (rs1800797, rs1800796 and rs1800795, respectively), which have been shown to affect both the transcription and secretion of IL-6, to symptomatic distal interphalan...

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Source

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Identifiers

PMID: 18257935
DOI: 10.1186/ar2374
PMCID: PMC2374458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18257935-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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