Article
COL2A1 gene polymorphisms and susceptibility to osteoarthritis of the hand in Finnish women.
Annals of the rheumatic diseases - 1 Oct 2009
Hämäläinen S, Solovieva S, Hirvonen A, Vehmas T, Takala E-P, Riihimäki H, Leino-Arjas P
Abstract excerpt
OBJECTIVES: To study the role of two COL2A1 single nucleotide polymorphisms (rs3737548 and rs2276455) and their haplotypes in individual susceptibility to osteoarthritis (OA) of the hand in Finnish women. METHODS: Bilateral hand radiographs of 543 Finnish female dentists and teachers aged 45-63 years were examined and classified for the presence of OA by using reference images. The COL2A1 genotypes were...
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