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Article

Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip.

Arthritis and rheumatism - 1 Apr 2004

Meulenbelt Ingrid, Seymour Albert B, Nieuwland Marja, Huizinga Tom W J, van Duijn Cornelia M, Slagboom P Eline

Abstract excerpt

OBJECTIVE: To study the role of the interleukin-1 beta gene (IL1B) and the IL-1 receptor antagonist gene (IL1RN) in relation to the occurrence of radiographic osteoarthritis (ROA) in the hip, knee, and hand and disc degeneration of the spine. METHODS: The study population consisted of a random sample of 886 subjects (ages 55-65 years) from a population-based cohort (the Rotterdam study). Two polymorphisms within...

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Identifiers

PMID: 15077300
DOI: 10.1002/art.20121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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