Article
Stem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in albino mice.
Pigment cell & melanoma research - 1 Dec 2009
Vanover Jillian C, Spry Malinda L, Hamilton Laura, Wakamatsu Kazumasa, Ito Shosuke, D'Orazio John A
Abstract excerpt
The K14-SCF transgenic murine model of variant pigmentation is based on epidermal expression of stem cell factor (SCF) on the C57BL/6J background. In this system, constitutive expression of SCF by epidermal keratinocytes results in retention of melanocytes in the interfollicular basal layer and p...
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