Article
The underwhite (uw) locus acts autonomously and reduces the production of melanin.
The Journal of investigative dermatology - 1 Oct 2000
Lehman A L, Silvers W K, Puri N, Wakamatsu K, Ito S, Brilliant M H
Abstract excerpt
The mouse has provided several significant models for hypopigmentation disorders, including the major forms of albinism. Mutations at the mouse underwhite locus confer one of the most severe hypopigmentation phenotypes, similar to mutations at the pink-eyed dilution locus that is a model for type 2 oculocutaneous albinism. A melanocyte cell line established from underwhite mutant mice failed to pigment under...
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