The Tyr (albino) locus of the laboratory mouse.

doi:10.1007/s00335-004-4002-8

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Article

The Tyr (albino) locus of the laboratory mouse.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2004

Beermann Friedrich, Orlow Seth J, Lamoreux M Lynn

Abstract excerpt

The albino mouse was already known in ancient times and was apparently selectively bred in Egypt, China, and Japan. Thus, it is not surprising that the c or albino locus (now the Tyr locus) was among the first used to demonstrate Mendelian inheritance in mammals at the dawn of the past century. This locus is now known to encode tyrosinase, the rate-limiting enzyme in the production of melanin pigment, and the...

Topics

Albinism
Alleles
Animals
Melanins
Mice
Mice, Transgenic
Monophenol Monooxygenase
Mutation

Source

Open in PubMed

Identifiers

PMID: 15520878
DOI: 10.1007/s00335-004-4002-8

Provenance

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