Article
Haplotype structure and allele frequencies of CYP2B6 in Spaniards and Central Americans.
Fundamental & clinical pharmacology - 1 Apr 2010
Arenaz Izaskun, Vicente Jorge, Fanlo Ana, Vásquez Patricia, Medina Juan Carlos, Conde Blanca, González-Andrade Fabricio, Sinués Blanca
Abstract excerpt
This study was aimed to investigate the potential differences in allele frequencies of the CYP2B6 gene between Spaniards and Central Americans. Three single nucleotide polymorphisms of the CYP2B6 gene 516 G>T, 785 A>G and 1459 C>T were assayed by a polymerase chain reaction in 180 Spaniards and 182 Central Americans. The allele frequencies for CYP2B6*1, CYP2B6*4, CYP2B6*5, CYP2B6*6, CYP2B6*9 in Spaniards and...
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