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Allelic and Genotype Frequencies of CYP2B6∗2 (64C > T) and CYP2B6∗3 (777C > A) in Three Dominant Ethnicities of the Iranian Population.

Genetics research - 1 Jan 2023

Khavandegar Armin, Tavakoli-Far Bahareh, Ansari Sarina, Veis-Karami Parisa, Ghasemi Faezeh, Sheibaninia Samira, Jazayeri Roshanak, Houshmand Massoud

Abstract excerpt

Background: Cytochrome P450 complex plays a key role in drug metabolism. CYP2B6 has an essential part in Cytochrome P450 complex metabolism. This study aims to determine the allelic distribution of CYP2B6∗2 and CYP2B6∗3 in three main Iranian ethnicities: Fars, Turk, and Kurd. Methods: The study was conducted on 174 unrelated healthy volunteers from three main Iranian ethnicities. After DNA extraction from...

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Identifiers

PMID: 36817260
DOI: 10.1155/2023/8283470
PMCID: PMC9934979

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