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Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 1 Sept 2006

Guan Su, Huang Min, Chan Eli, Chen Xiao, Duan Wei, Zhou Shu-Feng

Abstract excerpt

Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes more than eight compounds and about 3.0% of therapeutic drugs. The genetic polymorphisms of CYP2B6 have earlier been studied in Caucasian, Japanese and Korean, but the data are lacking for Han Chinese. The aim of this study was to investigate the frequencies of allelic variants of CYP2B6 in healthy Han Chinese and compare with those in other ethnic...

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PMID: 16815693
DOI: 10.1016/j.ejps.2006.04.004

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