Article
Frequencies of CYP2B6∗4,∗5, and ∗6 Alleles within an Iranian Population (Mazandaran).
Genetics research - 1 Jan 2021
Hashemi-Soteh Mohammad Bagher, Hosseini Elaheh, Fazelnia Shokoufeh, Ghasemian-Sorbeni Faramarz, Madahian Sara, Shiran Mohammad Reza
Abstract excerpt
Background: The human CYP2B subfamily consists of one functional gene (CYP2B6) and one pseudogene (CYP2B7P). Cytochrome P450 2B6 (CYP2B6) is a highly polymorphic enzyme that shows marked interindividual and interethnic variations. Currently, 38 alleles have been described, and some of the allelic variants have been associated with low enzyme activity. The aim of this study was to investigate the frequencies of...
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