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Article

Inositol 1,4,5- trisphosphate receptor function in Drosophila insulin producing cells.

PloS one - 14 Aug 2009

Agrawal Neha, Padmanabhan Nisha, Hasan Gaiti

Abstract excerpt

The Inositol 1,4,5- trisphosphate receptor (InsP(3)R) is an intracellular ligand gated channel that releases calcium from intracellular stores in response to extracellular signals. To identify and understand physiological processes and behavior that depends on the InsP(3) signaling pathway at a systemic level, we are studying Drosophila mutants for the InsP(3)R (itpr) gene. Here, we show that growth defects...

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Identifiers

PMID: 19680544
DOI: 10.1371/journal.pone.0006652
PMCID: PMC2721413

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