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Article

IP3R-mediated Ca2+ release regulates protein metabolism in Drosophila neuroendocrine cells: implications for development under nutrient stress.

Development (Cambridge, England) - 15 Apr 2017

Megha, Hasan Gaiti

Abstract excerpt

Successful completion of animal development is fundamentally reliant on nutritional cues. Surviving periods of nutritional insufficiency requires adaptations that are coordinated, in part, by neural circuits. As neuropeptides secreted by neuroendocrine (NE) cells modulate neural circuits, we investigated NE cell function during development under nutrient stress. Starved Drosophila larvae exhibited reduced...

Topics

Animals
Calcium
Calcium Signaling
Down-Regulation
Drosophila melanogaster
Food
Inositol 1,4,5-Trisphosphate Receptors
Intracellular Space
Larva
Mutation
Neuroendocrine Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Biosynthesis

Pupa

Receptor, Insulin

Stress, Physiological

Sucrose

Source

Open in PubMed Open full text

Identifiers

PMID: 28289132
DOI: 10.1242/dev.145235
PMCID: PMC5399668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28289132-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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