Article
The inositol 1,4,5-trisphosphate receptor is required for maintenance of olfactory adaptation in Drosophila antennae.
Journal of neurobiology - 5 Jun 2000
Deshpande M, Venkatesh K, Rodrigues V, Hasan G
Abstract excerpt
A role for inositol 1,4,5-trisphosphate (IP(3)) as a second messenger during olfactory transduction has been postulated in both vertebrates and invertebrates. However, given the absence of either suitable pharmacological reagents or mutant alleles specific for the IP(3) signaling pathway, an uneq...
Topics
- Action Potentials
- Adaptation, Physiological
- Alleles
- Animals
- Calcium Channels
- Drosophila
- Heterozygote
- Inositol 1,4,5-Trisphosphate Receptors
- Male
- Olfactory Pathways
- Point Mutation
- Receptors, Cytoplasmic and Nuclear
- Receptors, Odorant
- Signal Transduction
- Smell
- Time Factors