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Article

Genetic dissection of itpr gene function reveals a vital requirement in aminergic cells of Drosophila larvae.

Genetics - 1 Jan 2004

Joshi Rohit, Venkatesh K, Srinivas R, Nair Shalima, Hasan Gaiti

Abstract excerpt

Signaling by the second messenger inositol 1,4,5-trisphosphate is thought to affect several developmental and physiological processes. Mutants in the inositol 1,4,5-trisphosphate receptor (itpr) gene of Drosophila exhibit delays in molting while stronger alleles are also larval lethal. In a freshly generated set of EMS alleles for the itpr locus we have sequenced and identified single point mutations in seven...

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Identifiers

PMID: 15020420
DOI: 10.1534/genetics.166.1.225
PMCID: PMC1470716

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