Genetic dissection of itpr gene function reveals a vital requirement in aminergic cells of Drosophila larvae.

doi:10.1534/genetics.166.1.225

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genetic dissection of itpr gene function reveals a vital requirement in aminergic cells of Drosophila larvae.

Genetics - 1 Jan 2004

Joshi Rohit, Venkatesh K, Srinivas R, Nair Shalima, Hasan Gaiti

Abstract excerpt

Signaling by the second messenger inositol 1,4,5-trisphosphate is thought to affect several developmental and physiological processes. Mutants in the inositol 1,4,5-trisphosphate receptor (itpr) gene of Drosophila exhibit delays in molting while stronger alleles are also larval lethal. In a fresh...

Topics

Alleles
Animals
Animals, Genetically Modified
Calcium Channels
Cold Temperature
DNA, Complementary
Dopamine
Drosophila
Ethyl Methanesulfonate
Genes, Insect
Genes, Lethal
Inositol 1,4,5-Trisphosphate
Inositol 1,4,5-Trisphosphate Receptors
Larva
Mutagens
Phenotype
Point Mutation
Receptors, Cytoplasmic and Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 15020420
DOI: 10.1534/genetics.166.1.225
PMCID: PMC1470716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15020420-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics