Article
Inositol 1,4,5-trisphosphate receptor and dSTIM function in Drosophila insulin-producing neurons regulates systemic intracellular calcium homeostasis and flight.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Jan 2010
Agrawal Neha, Venkiteswaran Gayatri, Sadaf Sufia, Padmanabhan Nisha, Banerjee Santanu, Hasan Gaiti
Abstract excerpt
Calcium (Ca(2+)) signaling is known to regulate the development, maintenance and modulation of activity in neuronal circuits that underlie organismal behavior. In Drosophila, intracellular Ca(2+) signaling by the inositol 1,4,5-trisphosphate receptor and the store-operated channel (dOrai) regulat...
Topics
- Animals
- Calcium
- Calcium Signaling
- Cell Membrane
- Cells, Cultured
- Central Nervous System
- Drosophila
- Drosophila Proteins
- Flight, Animal
- Homeostasis
- Inositol 1,4,5-Trisphosphate Receptors
- Insulin
- Insulin Secretion