Article
Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.
Journal of gastroenterology and hepatology - 1 May 2005
Tahara Toshiyuki, Inoue Nagamu, Hisamatsu Tadakazu, Kashiwagi Kazuhiro, Takaishi Hiromasa, Kanai Takanori, Watanabe Mamoru, Ishii Hiromasa, Hibi Toshifumi
Abstract excerpt
BACKGROUND AND AIM: Although molecular mechanisms underlying ulcerative colitis (UC)-associated neoplasms have been studied for years, understanding of these mechanisms remains incomplete and no good predictable marker for development of colonic neoplasms in patients with UC has been established. The aim of this study was to assess if microsatellite instability (MSI) contributes to the development of colonic...
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