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Article

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.

Proceedings of the National Academy of Sciences of the United States of America - 11 Aug 2009

Liem Karel F, He Mu, Ocbina Polloneal Jymmiel R, Anderson Kathryn V

Abstract excerpt

Mammalian Sonic hedgehog (Shh) signaling is essential for embryonic development and stem cell maintenance and has critical roles in tumorigenesis. Although core components of the Shh pathway are conserved in evolution, important aspects of mammalian Shh signaling are not shared with the Drosophil...

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Identifiers

PMID: 19666503
DOI: 10.1073/pnas.0906944106
PMCID: PMC2726420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19666503-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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