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Article

A comparison of nerve growth factor binding protocols with native and mutant PC12 cells.

Neurochemical research - 1 Dec 1990

Kasaian M T, Neet K E

Abstract excerpt

A comparison has been made of various methods for measuring binding of nerve growth factor (NGF) to PC12 cells in suspension, on plates, and by a combination of the two. Results indicated that the extensive washing in the plate binding assay removed some cell surface ligand, underestimated the fast receptor binding, and overestimated the proportion of internalized ligand. In addition, the binding and...

Topics

Adrenal Gland Neoplasms
Animals
Cell Line
Kinetics
Mutation
Nerve Growth Factors
Pheochromocytoma
Rats
Receptors, Cell Surface
Receptors, Nerve Growth Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1965856
DOI: 10.1007/BF01208576

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1965856-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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