Article
Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma.
British journal of cancer - 1 Sept 2009
Bauer J, Kilic E, Vaarwater J, Bastian B C, Garbe C, de Klein A
Abstract excerpt
BACKGROUND: Recently, oncogenic G protein alpha subunit q (GNAQ) mutations have been described in about 50% of uveal melanomas and in the blue nevi of the skin. METHODS: GNAQ exon 5 was amplified from 75 ciliary body and choroidal melanoma DNAs and sequenced directly. GNAQ mutation status was cor...
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