Article
Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.
Anticancer research - 1 Oct 2017
Psinakis Filippos, Katseli Anastasia, Koutsandrea Chryssanthy, Frangia Konstantina, Florentin Lina, Apostolopoulou Despina, Dimakopoulou Konstantina, Papakonstantinou Dimitrios, Georgopoulou Eleni, Brouzas Dimitrios
Abstract excerpt
BACKGROUND/AIM: Uveal melanoma is the most common primary adult intraocular malignancy. It is known to have a strong metastatic potential, fatal for the vast majority of patients. In recent years, meticulous cytogenetic and molecular profiling has led to precise prognostication, that unfortunately is not matched by advancements in adjuvant therapies. G Protein subunits alpha Q (GNAQ) and alpha 11 (GNA11) are two...
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