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Article

Mutational profile of GNAQQ209 in human tumors.

PloS one - 31 Aug 2009

Lamba Simona, Felicioni Lara, Buttitta Fiamma, Bleeker Fonnet E, Malatesta Sara, Corbo Vincenzo, Scarpa Aldo, Rodolfo Monica, Knowles Margaret, Frattini Milo, Marchetti Antonio, Bardelli Alberto

Abstract excerpt

BACKGROUND: Frequent somatic mutations have recently been identified in the ras-like domain of the heterotrimeric G protein alpha-subunit (GNAQ) in blue naevi 83%, malignant blue naevi (50%) and ocular melanoma of the uvea (46%). The mutations exclusively affect codon 209 and result in GNAQ const...

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Share to Cutaneous Melanoma Detection and Management
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19718445
DOI: 10.1371/journal.pone.0006833
PMCID: PMC2730032

Genes

GNAQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19718445-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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