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Article

HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia.

Bone - 1 Dec 2009

Hwang Joo-Yeon, Lee Seung Hun, Kim Ghi Su, Koh Jung-Min, Go Min Jin, Kim Young-Jin, Kim Hyung-Cheol, Kim Tae-Ho, Hong Jung Min, Park Eui Kyun, Lee Jong-Young, Kim Shin-Yoon

Abstract excerpt

INTRODUCTION: Endogenous glucocorticoid (GC) may participate in bone physiology, even in subjects with no glucocorticoid excess. 11beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) is a primary regulator catalyzing the reduction of inactive cortisone to active cortisol. To elucidate genetic relevance of HSD11B1 variants to vertebral fracture and osteoporosis, we investigated the potential involvement of six...

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PMID: 19651257
DOI: 10.1016/j.bone.2009.07.080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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