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Article

Association between 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in Bosnian population.

Biochemia medica - 1 Jan 2012

Dujic Tanja, Bego Tamer, Mlinar Barbara, Semiz Sabina, Malenica Maja, Prnjavorac Besim, Ostanek Barbara, Marc Janja, Causevic Adlija

Abstract excerpt

INTRODUCTION: The enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) catalyzes the conversion of the hormonally inactive cortisone to active cortisol, thus facilitating glucocorticoid receptor activation in target tissues. Increased expression of 11beta-HSD1 in adipose tissue has been associated with obesity and insulin resistance. In this study, we investigated the association of two 11beta-HSD1...

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Identifiers

PMID: 22384521
PMCID: PMC4062331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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