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Article

The rs4844880 polymorphism in the promoter region of the HSD11B1 gene associates with bone mineral density in healthy and postmenopausal osteoporotic women.

Steroids - 1 Nov 2012

Feldman Karolina, Szappanos Agnes, Butz Henriett, Grolmusz Vince, Majnik Judit, Likó István, Kriszt Balázs, Lakatos Péter, Tóth Miklós, Rácz Károly, Patócs Attila

Abstract excerpt

INTRODUCTION: The 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1) plays an important role in the regulation of local glucocorticoid concentration in a tissue specific manner. Previous studies indicated associations between polymorphisms (SNPs) of the HSD11B1 gene and laboratory as well as osteodensitometric parameters of bone metabolism. In our present work we examined whether the tagging HSD11B1 gene...

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PMID: 22986073
DOI: 10.1016/j.steroids.2012.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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