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Article

Association of Three Single Nucleotide Polymorphisms in MTR and MTRR Genes with Lung Cancer in a Turkish Population.

Genetic testing and molecular biomarkers - 1 Jul 2017

Aksoy-Sagirli Pinar, Erdenay Ayçin, Kaytan-Saglam Esra, Kizir Ahmet

Abstract excerpt

AIMS: Folate metabolism plays a critical role in DNA methylation and synthesis. Polymorphisms in folate metabolism may affect enzyme activities and thereby affect the cancer risk. Methionine synthase (MTR) and methionine synthase reductase (MTRR) are critical enzymes for the folate cycle. In this study, possible associations between genetic variabilities in MTR and MTRR and susceptibility to lung cancer (LC) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28537809
DOI: 10.1089/gtmb.2017.0062

Genes

MTRR
MTR

Variants

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