Article
Prognostic significance of folate metabolism polymorphisms for lung cancer.
British journal of cancer - 16 Jul 2007
Matakidou A, El Galta R, Rudd M F, Webb E L, Bridle H, Eisen T, Houlston R S
Abstract excerpt
Functional nonsynonymous single-nucleotide polymorphisms (nsSNPs) of folate metabolism genes can influence the methylation of tumour suppressor genes, thereby potentially impacting on tumour behaviour. To investigate whether such polymorphisms influence lung cancer survival, we genotyped 14 nsSNP...
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